Prof Rob (R. C.) Aalberse PhD

Thesis

'IgE, allergens and their interaction'
1974 - University of Amsterdam

Research interests

Antibodies, antigens and B cells involved in the TH2 immune response. The focus is on the B cell response to 'weak' antigens, i.e. antigens lacking signals that activate the innate immune system. The working hypothesis is that such an immune response is less tightly regulated. The IgE response to classical atopic allergens (pollen, mites, etc) is considered to be a prototypic example.

Technology

Immunochemical and biochemical procedures related to antigens and antibodies (natural and recombinant), including radioimmunoassays for antibodies, allergens and other antigens; in-silico analysis of the structure of antibodies and allergens.

Resume

1990-2010	Professor of Immunology, University of Amsterdam
1986	Visiting Associate Professor, University of Virginia (USA), division of Allergy (Head: TAE Platts-Mills PhD)
1979-2009	Head Allergy/Immunochemistry at CLB/Sanquin
1974	PhD training at the Dept of Immunopathology of serum proteins at CLB/Sanquin