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Chapters

Red Blood Cell Transfusion in Sickle Cell Disease

Download thesis (university repository, when available)

Chapter 1

General introduction and outline of the thesis

PART I: What is the effect of genetic polymorphisms on red blood cell alloimmunization risk?

Chapter 2

Identification of genetic biomarkers for alloimmunization in sickle cell disease. abstract

Chapter 3

Back to Base Pairs; What is the Genetic Risk for Red Blood Cell Alloimmunization? abstract

PART II: Unraveling the black box: The effect and side effects of red blood cell transfusions in sickle cell disease and 13-thalassemia

Chapter 4

Measurement of survival of transfused red blood cells in patients with Sickle cell disease and -Thalassemia, a biotin label approach.

Chapter 5

Red Blood Cell Transfusion does not Elicit an Innate Immune Reaction in Chronically Transfused Patients with Sickle Cell Disease and 3-thalassemia.

Chapter 6

Extended Phenotyping Does Not Preclude the Occurrenceof Delayed Haemolytic Transfusion Reactions in Sickle Cell Disease. abstract


Chapter 7

Discussion and Future perspectives