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Chapters

The Weibel-Palade body from formation to fireworks

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Chapter 1

General introduction

Chapter 2


Exocytosis of Weibel-Palade bodies: How tounpack a vascular emergency kit Abstract

Chapter 3

Alternative trafficking of Weibel-Palade body in CRISPR/Cas9-engineered von Willebrand factor-deficient blood outgrowth endothelial cells Abstract

Chapter 4

Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture Abstract

Chapter 5

GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies Abstract

Chapter 6

NBEAL2 mutations do not impact Weibel-Palade body biogenesis and exocytosis in Gray Platelet Syndrome endothelial cells

Chapter 7

Dispatch and delivery at the ER - Golgi interface: how endothelial cells tune their hemostatic response

Chapter 8

General Discussion