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Chapters

Going beyond your form: T-cell dependent B-cell fate determination

Download thesis from university repository (when available)

Chapter 1

General introduction and outline of the thesis

Chapter 2

System-level scenarios for the elucidation of T cell-mediated germinal center B cell differentiation abstract

Chapter 3

Human B cells engage the NCK/PI3K/RAC1 axis to internalize large particles via the IgM-BCR abstract

Chapter 4

TCR signal strength regulates the plastic co-expression of IL-4 and IFN-y by Tfh-like cells

Chapter 5

Minimalistic in vitro culture to drive human naive B cell differentiation into antibody-secreting cells abstract

Chapter 6

Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates abstract

Chapter 7

Summarizing discussion