Chapters
Shaping neutrophil responses against cancer: the role of integrin regulationDownload thesis from university repository (when available)
Chapter 1
General introduction
PART I: lntegrin regulation in neutrophil host defense
Chapter 2
β2 integrin signaling cascade in neutrophils: more than a single function abstract
Chapter 3
SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function abstract
PART II: Neutrophil cytotoxicity towards tumor cells: unleashing the brakes
Chapter 4
KINDLIN3-dependent CD11b/CD18-integrin activation is required for potentiation of neutrophil cytotoxicity by CD47-SIRPα checkpoint disruption abstract
Chapter 5
The sialic acid-SIGLEC axis limits neutrophil ADCC against solid tumors through regulation of the CD11b/CD18 integrin affinity abstract
Chapter 6
Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex abstract
Chapter 7
General discussion