Chapters
Influence of immunoglobulin G-glycan and subclass variation on antibody effector functionsChapter 1
General introduction and scope of the thesis
Chapter 2
Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans. abstract
Chapter 3
Decoding the human IgG-glycan repertoire reveals a spectrum of Fc-receptor- and complementmediated-effector activities
Chapter 4
Inhibition of FcγR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcγRIIb in human macrophages. abstract
Chapter 5
Enhanced effector functions due to antibody defucosylation depend on the effector cell Fcγ receptor profile. abstract
Chapter 6
Affinity of human IgG subclasses to mouse Fc gamma receptors. abstract
Chapter 7
Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice
Chapter 8
Hinge-region O-glycosylation of human immunoglobulin G3 (IgG3). abstract
Chapter 9
General discussion
