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Chapters

Alloimmunization after platelet transfusion: mechanisms, prevention and treatment

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Chapter 1

General introduction and scope of the thesis

Chapter 2

The quality of platelet concentrates related to corrected count increment: linking in vitro to in vivo

Chapter 3

Storage-induced platelet apoptosis is a potential risk factor for alloimmunization upon platelet transfusion Abstract

Chapter 4

The role of pathogen-reduced platelet transfusions on HLA alloimmunization in hemato-oncological patients

Chapter 5

Platelets from donors with consistent low HLA-B8, B12 or B35 expression do not undergo antibody-mediated internalization Abstract

Chapter 6

Platelet degranulation inhibits pro-inflammatory capacities of TLR-stimulated DCs

Chapter 7

General discussion