Chapters
Setting the scale: The balance between complement factor H and its related proteins in health and diseaseChapter 1
General introduction and scope of this thesis
Chapter 2
Characterization of novel anti-factor H antibodies reveals the role of factor H in protecting human erythrocytes from complement
Chapter 3
Antibody-mediated potentiation of complement regulator factor H protects human endothelial cells from complement attack in aHUS sera
Chapter 4
Complement factor H-related protein 3 serum levels are low compared to factor H and mainly determined by gene copy number variation in CFHR3 Abstract
Chapter 5
Complement factor H-related protein 4A is the dominant circulating splice variant of CFHR4 Abstract
Chapter 6
High complement factor H-related (FHR)-3 levels are associated with the atypical hemolytic uremic syndrome-risk allele CFHR3*B Abstract
Chapter 7
Variation in the CFHR3 gene determines susceptibility to meningococcal disease by controlling factor H levels
Chapter 8
Complement factor H and factor H-related protein 3 levels during infectious meningococcal disease
Chapter 9
Summarizing discussion
