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Chapters

The Versatility of Mesenchymal Stromal Cells - Means for Optimization

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Chapter 1 

General Introduction and Scope of the Thesis

Parts adapted from Munneke JM, Spruit MJ, Cornelissen AS, van Hoeven V, Voermans C, Hazenberg MD. The Potential of Mesenchymal Stromal Cells as Treatment for Severe Steroid-Refractory Acute Graft-Versus-Host Disease: A Critical Review of the Literature’. Transplantation. 2016, 100 (11): 2309-2314. Abstract

Chapter 2 

Organ-specific Migration of Mesenchymal Stromal Cells: Who, When, Where and Why?  Abstact

Chapter 3 

Migratory Behaviour and Biodistribution of Human Mesenchymal Stromal Cells is Limited by Imbalanced Nuclear-Cytoskeletal Coupling


Chapter 4 

Means to Optimize Mesenchymal Stromal Cel ls for Immunomodulation

Chapter 5 

Interferon-gamma Impairs Maintenance and Al ters Hematopoietic Support of Bone Mar row Mesenchymal Stromal Cells Abstract


Chapter 6

Mesenchymal Stromal Cel ls Stimulate the Proliferation and Inter leukin-22 Production of Group 3 Innate Lymphoid Cells Abstract

Chapter 7

Nucleosome Levels are Increased in Acute Graft-versus-Host Disease in Patients and Mice

Chapter 8

General Discussion