Chapters
Regulation of complement activation on red blood cellsChapter 1
Introduction and scope of this thesis
Chapter 2
Consequences of dysregulated complement regulators on red blood cells Abstract
Chapter 3
Complement regulator CD46 expression is lost gradually during erythropoiesis and enucleation
Chapter 4
Complement deposition and IgG binding on stored red blood cells are independent of storage time
Chapter 5
Blocking the binding region domains 6-8 of factor H inhibits its complement regulation function on human red blood cells
Chapter 6
CRISPR/Cas9 generated human CD46, CD55 and CD59 knockout cell lines as a tool for complement research Abstract
Chapter 7
The amplification loop is not required for efficient classical complement pathway activation
Chapter 8
Summarizing discussion
