Chapters

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Part 1: Overview

General Introduction

Chapter 1 

Intrauterine transfusion and non-invasive treatment options for hemolytic disease of the fetus and newborn - review on current
management and outcome Abstract

Part 2: pathogenesis and severity of hemolytic disease of the fetus and newborn

Chapter 2 

ABO incompatibility and RhIg immunoprophylaxis protect against non-D alloimmunization by pregnancy Abstract

Chapter 3

Does disease severity always increase in subsequent pregnancies with D immunization?

Chapter 4 

The near disappearance of fetal hydrops in relation to current state-of-the-art management of red cell alloimmunization Abstract

Part 3: intrauterine transfusion and other treatment options

Chapter 5 

Complications of intrauterine intravascular blood transfusion: lessons learned after 1678 procedures Abstract

Chapter 6

Postponing Early intrauterine Transfusion with Intravenous immunoglobulin Treatment; the PETIT study on severe hemolytic disease of
the fetus and newborn Abstract

Chapter 7 

Immunoglobulin for alloimmune hemolytic disease in neonates – a Cochrane review Abstract

Part 4: summary and discussion

Summary and General Discussion