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Chapters

Challenges in platelet transfusion; from storage to alloimmunization

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Chapter 1

General introduction

Chapter 2

Evaluation of the role of the GPIb-IX-V receptor complex in development of the platelet storage lesion. abstract

Chapter 3

Monitoring storage induced changes in the platelet proteome employing label free quantitative mass spectrometry. abstract

Chapter 4

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation. abtract

Chapter 5

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets. abstract

Chapter 6

General discussion