Chapters
When it’s not a match; cellular and genetic factors in alloantibody-mediated red blood cell clearanceChapter 1
General introduction and scope of this thesis
Part I - Neutrophils in IgG-mediated RBC clearance
Chapter 2
Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells Abstract
Chapter 3
Neutrophils acquire antigen presenting cell features after phagocytosis of IgG-opsonized erythrocytes Abstract
Part II - Genetic markers for alloimmunization in sickle cell disease
Chapter 4
Non-classical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease Abstract
Chapter 5
Identification of genetic biomarkers for alloimmunization in sickle cell disease
Chapter 6
Summary and general discussion
