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Chapters

Localization, phenotype and function of CD8+ T cells in the bone marrow

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Chapter 1

General Introduction

Chapter 2

Quantitative and qualitative analysis of bone marrow CD8+ T cellsccfrom different bones uncovers a major contribution of the bone marrow in the vertebrae Abstract

Chapter 3

CD69+ memory CD8+ T cells in the bone marrow are a unique subset of resident, quiescent, poly-functional memory T cells, which is dependent on IL-15 and Hobit, but not on local antigen recognition

Chapter 4

Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow abstract

Chapter 5

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection Abstract

Chapter 6

General Discussion